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pH-Responsive Polymersome Microparticles as Smart Cyclodextrin-Releasing Agents Just Accepted in Bio


I am overjoyed to have had my latest paper just accepted for publication in Biomacromolecules. In this work I lay out my core hypothesis about the overall project, that is, I can fabricate a CD-based polymersome system which is stable under physiological conditions and it disassembles at acidic pH. Some preliminary biological assays such as cytotoxcitiy and cellular uptake are presented.

I am conscious of the fact that this is still quite a way far from demonstrating lysosomal delivery of CDs but I think it is very encouraging and definitely a step forward in that direction.

I am very grateful to the co-authours of this all-Turkish work: prof Yagci (ITU), prof Timur (Ege Uni) and the fantastic Dr Ece Bayir (Ege Uni).

I am not looking forward to investigating further the biological activities of this system together with the other collaborators


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